Table 7 Association of EGFR exon 21 del with studied parameter
EGFR (exon 21) rs121434568 | Wild genotype | Mutant genotype | P | |||
|---|---|---|---|---|---|---|
TT | TG + GG | |||||
n | % | n | % | |||
Pathology | Adenocarcinoma | 60 | 74.1% | 38 | 88.4% | 0.063 |
large cell carcinoma | 7 | 8.6% | 5 | 11.6% | 0.751 | |
squamous cell | 8 | 9.9% | 0 | 0.0% | 0.049 | |
Others | 6 | 7.4% | 0 | 0.0% | 0.092 | |
Grade | 1 | 0 | 0.0% | 2 | 4.7% | 0.241 |
2 | 27 | 35.1% | 14 | 32.6% | ||
3 | 50 | 64.9% | 27 | 62.8% | ||
Stage | I | 2 | 2.5% | 0 | 0.0% | 0.448 |
II | 2 | 2.5% | 1 | 2.3% | ||
III | 19 | 23.5% | 6 | 14.0% | ||
IV | 58 | 71.6% | 36 | 83.7% | ||
Tumor cytochemistry | TTF1 | 37 | 45.7% | 27 | 62.8% | 0.070 |
CK7 | 54 | 66.7% | 34 | 79.1% | 0.148 | |
napsin A | 25 | 30.9% | 17 | 39.5% | 0.332 | |