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Table 3 Induced micronuclei in vivo

From: Carcinogenic risk of food additive AF-2 banned in Japan: a case study on reassessment of genotoxicity

Treatment

Dose

MNRETs per 1000RETs

Mean ± SD (%)

First 48 h

   

 Olive oil

10 mL/kg

0

3

1

2

0.15 ± 0.11

 AF-2

120 mg/kg

1

3

2

5

0.28 ± 0.15

 DBP (positive control)

6 mg/kg

11

2

3

11

0.68 ± 0.43

Second 48 h

      

 Olive oil

10 mL/kg

1

3

0

3

0.18 ± 0.13

 AF-2

120 mg/kg

0

1

2

1

0.10 ± 0.07

 DBP (positive control)

6 mg/kg

8

68

53

52

4.53 ± 2.24