Skip to main content

Articles

Page 5 of 6

  1. The high-fidelity transmission of genetic information is crucial for the survival of organisms, the cells of which have the ability to protect DNA against endogenous and environmental agents, including reactiv...

    Authors: Sayoko Ito-Harashima and Takashi Yagi
    Citation: Genes and Environment 2017 39:28
    Content type: Review Published on:

  2. The open symposium of the Japanese Environmental Mutagen Society (JEMS) titled, “Research on Environmental Mutagenesis from Young Scientists,” was held at Kokusai Kenkyu Koryu Kaikan, the Foundation for Promot...

    Authors: Kenichi Masumura and Shuichi Masuda
    Citation: Genes and Environment 2017 39:26
    Content type: Meeting report Published on:

  3. The adverse effects of Asian dust (AD) on health have been demonstrated in earlier studies, but there is no standardized definition for heavy–AD. This study aimed to examine which definition of heavy–AD has th...

    Authors: Jun Kurai, Masanari Watanabe, Hisashi Noma, Kyoko Iwata, Jumpei Taniguchi, Hiroyuki Sano, Yuji Tohda and Eiji Shimizu
    Citation: Genes and Environment 2017 39:25
    Content type: Research Published on:

  4. The commonly consumed antioxidants β-carotene and tea polyphenols were used to assess their protective effects against γ-radiation induced sex-linked recessive lethal (SLRL) mutation and oxidative stress in Droso...

    Authors: Isha Nagpal and Suresh K. Abraham
    Citation: Genes and Environment 2017 39:24
    Content type: Research Published on:

  6. Blackcurrant (Ribs nigrum L.) is a classical fruit that has long been used to prepare juice, jam, liqueur, and sometimes medicines in Europe. Previously, we reported a genome defense effect by the antioxidative a...

    Authors: Ayumi Yamamoto, Tokuhisa Hirouchi, Saori Kawamorita, Kana Nakashima, Atena Sugiyama and Yoji Kato
    Citation: Genes and Environment 2017 39:22
    Content type: Short report Published on:

  7. Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication. 8-Oxo-7,8-dihydroguanine (8-oxoG) causes G:C-T:A tran...

    Authors: Katsuhito Kino, Masayo Hirao-Suzuki, Masayuki Morikawa, Akane Sakaga and Hiroshi Miyazawa
    Citation: Genes and Environment 2017 39:21
    Content type: Review Published on:

  8. Recently, Asian dust (AD) has become a serious health problem and several studies have clearly proven that AD can aggravate asthma. However, it remains unclear as to which components of AD have a strong effect...

    Authors: Kyoko Iwata, Masanari Watanabe, Jun Kurai, Naoto Burioka, Sachiko Nakamoto, Degejirihu Hantan and Eiji Shimizu
    Citation: Genes and Environment 2017 39:19
    Content type: Research Published on:

  9. Genetic and environmental risk factors play an important role for the susceptibility to sporadic Parkinson’s disease (PD). It was hypothesized that a splice variant of the CYP2D6 gene (CYP2D6*4 allele) is associa...

    Authors: Anwarullah, Muhammad Aslam, Mazhar Badshah, Rashda Abbasi, Aneesa Sultan, Kafaitullah Khan, Nafees Ahmad and Jakob von Engelhardt
    Citation: Genes and Environment 2017 39:18
    Content type: Research Published on:

  11. Pefcalcitol, an analog of vitamin D3 (VD3), is an anti-psoriatic drug candidate that is designed to achieve much higher pharmacological effects, such as keratinocyte differentiation, than those of VD3, with fewer...

    Authors: Akira Takeiri, Kenji Tanaka, Asako Harada, Kaori Matsuzaki, Mariko Yano, Shigeki Motoyama, Chie Katoh and Masayuki Mishima
    Citation: Genes and Environment 2017 39:17
    Content type: Research Published on:

  12. Kaolin is white clay mineral with the chemical composition Al2Si2O5(OH)4, and many varieties of kaolins having different crystal structures are utilized in industrial, cosmetic and medical fields. To evaluate the...

    Authors: Tatsuya Kato, Tatsushi Toyooka, Yuko Ibuki, Shuichi Masuda, Masatoshi Watanabe and Yukari Totsuka
    Citation: Genes and Environment 2017 39:12
    Content type: Research Published on:

  16. The Japanese Environmental Mutagen Society (JEMS) was established in 1972 by 147 members, 11 of whom are still on the active list as of May 1, 2016. As one of them, I introduce some historic topics here. These...

    Authors: Shizuyo Sutou
    Citation: Genes and Environment 2017 39:9
    Content type: Letter to the Editor Published on:

  18. The evolution of methods to assess genotoxicity of test compounds is thought to be one of the important subjects in The Japanese Environmental and Mutagen Society (JEMS). In 1970, the Ministry of Education of...

    Authors: Toshio Sofuni
    Citation: Genes and Environment 2017 39:15
    Content type: Letter to the Editor Published on:

  19. Rats are a standard experimental animal for cancer bioassay and toxicological research for chemicals. Although the genetic analyses were behind mice, rats have been more frequently used for toxicological resea...

    Authors: Takehiko Nohmi, Kenichi Masumura and Naomi Toyoda-Hokaiwado
    Citation: Genes and Environment 2017 39:11
    Content type: Review Published on:

  21. Cytochrome P450 CYP1A1 helps detoxify the potential carcinogens in tobacco smoke, it was reported that polymorphisms in the coding gene result in variation in the expression and activity levels which alter met...

    Authors: Nada Ezzeldin, Dalia El-Lebedy, Amira Darwish, Ahmed El-Bastawisy, Mirhane Hassan, Shereen Abd El-Aziz, Mohamed Abdel-Hamid and Amal Saad-Hussein
    Citation: Genes and Environment 2017 39:7
    Content type: Research Published on:

  22. Interactions between genes and environment are critical factors for causing cancer in humans. The genotoxicity of environmental chemicals can be enhanced via the modulation of susceptible genes in host human c...

    Authors: Yuki Kanemaru, Tetsuya Suzuki, Akira Sassa, Kyomu Matsumoto, Noritaka Adachi, Masamitsu Honma, Satoshi Numazawa and Takehiko Nohmi
    Citation: Genes and Environment 2017 39:6
    Content type: Research Published on:

  23. A powdered ethanolic extract of Glycyrrhiza aspera root exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) based on the Ames assay with Salmonella typhimurium TA1535. The aim of this study was t...

    Authors: Keiko Inami, Yusuke Mine, Jin Tatsuzaki, Chihiro Mori and Masataka Mochizuki
    Citation: Genes and Environment 2017 39:5
    Content type: Research Published on:

  24. It is known that fibrous particles of micrometer length, such as carbon nanotubes, which have same dimensions as asbestos, are carcinogenic. Carcinogenicity of nanomaterials is strongly related to inflammatory...

    Authors: Katsuyoshi Horibata, Akiko Ukai, Akio Ogata, Dai Nakae, Hiroshi Ando, Yoshikazu Kubo, Akemichi Nagasawa, Katsuhiro Yuzawa and Masamitsu Honma
    Citation: Genes and Environment 2017 39:4
    Content type: Short report Published on:

  25. Infection and chronic inflammation have been recognized as important factors for carcinogenesis. Under inflammatory conditions, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated f...

    Authors: Shosuke Kawanishi, Shiho Ohnishi, Ning Ma, Yusuke Hiraku, Shinji Oikawa and Mariko Murata
    Citation: Genes and Environment 2017 38:26
    Content type: Review Published on:

  28. Guanine oxidation occurs in both DNA and the cellular nucleotide pool, and one of the major products is 8-hydroxyguanine (8-oxo-7,8-dihydroguanine). The mutagenic potentials of this oxidized base have been exa...

    Authors: Tetsuya Suzuki and Hiroyuki Kamiya
    Citation: Genes and Environment 2016 39:2
    Content type: Review Published on:

    The Erratum to this article has been published in Genes and Environment 2017 39:20

  29. Actinidia arguta, known as sarunashi in Japan, is a vine tree native to east-Asia, including Japan, that produces small fruit rich in anthocyanins, catechins, vitamin C, chlorophyll, b...

    Authors: Mari Nishimura, Yuma Okimasu, Naoko Miyake, Misako Tada, Ryoko Hida, Tomoe Negishi and Sakae Arimoto-Kobayashi
    Citation: Genes and Environment 2016 38:25
    Content type: Research Published on:

  30. We investigated the enhancing effect of metal ions on several mutagens and examined their mechanism of action. We performed the Ames tests on six mutagens, i.e., 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, 4-ni...

    Authors: Nobuyoshi Fujii, Shigemitsu Yano and Kenji Takeshita
    Citation: Genes and Environment 2016 38:21
    Content type: Research Published on:

  32. Carcinogens are known to cause swelling of the mammalian cell nucleus. However, the mechanism of the swelling and its toxicological significance have not been fully elucidated. Since nuclear swelling (NS herea...

    Authors: Kenji Takeshita, Hiroaki I. Ogawa and Toshinari Maeda
    Citation: Genes and Environment 2016 38:22
    Content type: Research Published on:

  34. Cytosine residues in CpG dinucleotides often undergo various types of modification, such as methylation, deamination, and halogenation. These types of modifications can be pro-mutagenic and can contribute to t...

    Authors: Akira Sassa, Yuki Kanemaru, Nagisa Kamoshita, Masamitsu Honma and Manabu Yasui
    Citation: Genes and Environment 2016 38:17
    Content type: Short report Published on:

  36. Toxicogenomics is a rapidly developing discipline focused on the elucidation of the molecular and cellular effects of chemicals on biological systems. As a collaborative study group of Toxicogenomics/JEMS·MMS,...

    Authors: Chie Furihata, Takashi Watanabe, Takayoshi Suzuki, Shuichi Hamada and Madoka Nakajima
    Citation: Genes and Environment 2016 38:15
    Content type: Review Published on:

  37. Cancer is now the leading cause of death in Japan. A rapid increase in cancer mortality is expected as Japan is facing a super-aged society. Many causes of cancer are known to be closely linked to life style f...

    Authors: Yasusei Kudo, Hidesuke Tada, Natsumi Fujiwara, Yoshiko Tada, Takaaki Tsunematsu, Yoichiro Miyake and Naozumi Ishimaru
    Citation: Genes and Environment 2016 38:13
    Content type: Review Published on:

  40. The editors of Genes and Environment would like to thank all our reviewers who have contributed to the journal in Volume XXXVII (2015).

    Authors: Takashi Yagi
    Citation: Genes and Environment 2016 39:1
    Content type: Reviewer acknowledgement Published on:

    The Erratum to this article has been published in Genes and Environment 2017 39:20

  41. The linear no-threshold model (LNT) has been the basis for radiation protection policies worldwide for 60 years. LNT was fabricated without correct data. The lifespan study of Atomic bomb survivors (LSS) has p...

    Authors: Shizuyo Sutou
    Citation: Genes and Environment 2016 38:12
    Content type: Commentary Published on:

  42. The mucosal immune system is unique to the gastrointestinal mucosa, in which a large number of immune cells are located and exert multiple functions. Meanwhile, ~100 trillion microorganisms are thought to co-i...

    Authors: Mayuko Yamamoto and Satoshi Matsumoto
    Citation: Genes and Environment 2016 38:11
    Content type: Review Published on:

  45. Germline mutations are heritable and may cause health disadvantages in the next generation. To investigate trans-generational mutations, we treated male gpt delta mice with N-ethyl-N-nitrosourea (ENU) (85 mg/kg i...

    Authors: Kenichi Masumura, Naomi Toyoda-Hokaiwado, Akiko Ukai, Yoichi Gondo, Masamitsu Honma and Takehiko Nohmi
    Citation: Genes and Environment 2016 38:10
    Content type: Research Published on:

  46. Evidence from epidemiological and experimental studies has shown that non-steroidal anti-inflammatory drugs (NSAIDs) reduce the risk of colorectal cancer (CRC). The function of NSAIDs and the molecular targets...

    Authors: Takahiro Hamoya, Gen Fujii, Shingo Miyamoto, Mami Takahashi, Yukari Totsuka, Keiji Wakabayashi, Jiro Toshima and Michihiro Mutoh
    Citation: Genes and Environment 2016 38:6
    Content type: Review Published on:

  47. Pesticide exposure possesses risk of genotoxicity to humans, particularly farmers. Despite accumulating evidences linking genotoxicity to pesticide exposure, epidemiological studies to address pesticide toxici...

    Authors: Zariyantey Abdul Hamid, Mohd Faizal Mohd Zulkifly, Asmah Hamid, Syarif Husin Lubis, Nihayah Mohammad, Ismarulyusda Ishak, Nur Zakiah Mohd Saat, Hidayatul Fathi Othman, Ahmad Rohi Ghazali, Mohd Jamil Mohd Rafaai, Mohamad Roff Mohd Noor and Nor Fadilah Rajab
    Citation: Genes and Environment 2016 38:7
    Content type: Research Published on:

  48. The study was carried out to identify the polymorphisms in mitochondrial genes (ATPase and ND1) in type 2 Diabetes Mellitus (T2DM) from Mizo population and to correlate the involvement of demographic factors.

    Authors: Freda Lalrohlui, Sunaina Thapa, Souvik Ghatak, John Zohmingthanga and Nachimuthu Senthil Kumar
    Citation: Genes and Environment 2016 38:5
    Content type: Short report Published on:

  50. Several alkenylbenzenes, including methyleugenol (ME), are present in a wide range of botanicals and exhibit carcinogenic and mutagenic properties. Negative results are generally obtained for alkenylbenzenes i...

    Authors: Hiroshi Honda, Kazuyuki Minegawa, Yurika Fujita, Noriko Yamaguchi, Yoshihiro Oguma, Hansruedi Glatt, Naohiro Nishiyama and Toshio Kasamatsu
    Citation: Genes and Environment 2016 38:1
    Content type: Short report Published on:

Genes and Environment is an official journal of The Japanese Environmental Mutagen and Genome Society (JEMS).

JEMS logo
Submit manuscript

2022 Citation Impact
1.7 - 2-year Impact Factor
1.9 - 5-year Impact Factor
0.563 - SNIP (Source Normalized Impact per Paper)
0.537 - SJR (SCImago Journal Rank)

2022 Speed
8 days submission to first editorial decision for all manuscripts (Median)
94 days submission to accept (Median)

2022 Usage 
188,720 downloads
578 Altmetric mentions

Follow

Genes and Environment

ISSN: 1880-7062

Contact us